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Each year a national survey of HIV prevalence among women attending public antenatal clinics in South Africa is conducted by the Department of Health. The Annual HIV antenatal survey provides South Africa with annual HIV trends among pregnant women and further provides the basis for making other estimates and projections on HIV/AIDS trends.

Sentinel sites were selected on the basis of a systematic random sampling in which weighting is conducted using the probability proportional to size (PPS) technique

The high HIV prevalence rates among pregnant women and the projected rates on the general population suggest the ever-increasing need for effective interventions and programmes and strengthening partnerships that will impact on the HIV/AIDS epidemic.