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How Soon after Infection with HIV Does the Risk of Tuberculosis Start to Increase? A Retrospective Cohort Study in South African Gold Miners

Non HST

 

Publication Information

1st Author : Sonnenberg, Pam
Other Authors: Glynn JR, Fielding K, Murray J, Godfrey-Faussett P, Shearer S
Publisher: Journal of Infectious Diseases
Publication Date: 0/2005
ISBN:
ISSN:
Publication Type: Journal
Series: Journal of Infectious Diseases
Issue: 2005

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Summary Infection with human immuodeficiency virus (HIV) increases the risk of tuberculosis (TB), but no study has assessed how this risk changes with time since HIV seroconversion.
More Details

The incidence of pulmonary TB was estimated in miners with and those without HIV infection in a retrospective cohort study. HIV test results were linked to routinely collected TB, demographic, and occupational data. The rate ratio (RR) for the association between HIV status and TB was estimated by time since HIV seroconversion, calendar period, and age.

The increase in the risk of TB so soon after infection with HIV was unexpected. Current predictive models of TB incidence underestimate the effect of HIV infection in areas where TB is endemic.

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Keywords This Item is associated with the Following Keywords: TB, HIV/AIDS.
   
   
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